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11 minutes ago, Colin said:

Some potentially good news out of Quebec, our local infection and hospital rate is doing pretty good out here on the wet coast.

https://montreal.ctvnews.ca/quebec-researchers-say-they-have-found-an-effective-drug-to-fight-covid-19-1.5279310

That's some of that dangerous off-label use of old drugs. To wit;

https://player.vimeo.com/video/404703032?dnt=1&app_id=122963

colchicine starts at about 3:47.

https://www.pharmacytimes.com/contributor/timothy-o-shea/2016/01/10-surprising-off-label-uses-for-prescription-medications

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Although the exact mechanism of colchicine is not fully understood, its anti-inflammatory effect for pericarditis appears to be related to its ability to inhibit microtubule self-assembly, resulting in decreased leucocyte motility and phagocytosis.

https://www.healio.com/news/cardiology/20130208/10_3928_1081_597x_20130101_01_1020572

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Although the exact mechanism of action of colchicine has not been definitively established, its effects are thought to be mediated through an interruption in the activation of inflammatory mediators associated with neutrophils and monocytes, as well as disruption of leukocyte function, ultimately resulting in anti-inflammatory effects. Indications for which colchicine have been explored beyond gout and FMF include prevention of pericarditis events and, more recently, prevention of atrial fibrillation and CV events.

Pericarditis seems to be a frequent side-effect of COVID-19 infection;

https://www.acc.org/Latest-in-Cardiology/Articles/2020/09/25/17/22/COVID-19-Myopericarditis

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Pericardial fluid is typically exudative and free of virus, therefore likely representing an inflammatory, rather than infectious process. Furthermore, the degree of pericardial inflammatory response (and therefore size/volume of effusion) does not necessarily correlate with the degree of myocardial involvement, i.e. a large pericardial effusion with tamponade can be seen in the absence of severe/fulminant myocarditis.

Not sure what the bleep the above paragraph says, but I am guessing that pericarditis is a sometimes knock-on effect to COVID-19 infection. I would speculate that effusion and/or inflammation of the pericardium has an adverse effect on cardiac efficiency and therefore blood ox saturation.

 

 

 

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https://www.usatoday.com/story/news/health/2021/01/23/covid-cases-updates-larry-king-dies-after-being-hospitalized-covid-19/6674844002/

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California Gov. Gavin Newsom's administration won’t disclose key information that will help determine when his latest stay-at-home order is lifted.

 

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https://www.cnn.com/2021/01/21/health/covid-19-monoclonal-antibody-treatment-neglected/index.html
 

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In Michigan, for example, less than 10% of available Covid-19 monoclonal antibody treatments have been used, Dr. William Fales, the medical director at the Michigan Department of Health and Human Services, said during a news briefing last week.


California health officials told CNN that facilities in their state had administered 8% of monoclonal antibody stock on hand during the week of January 13.

 

 

 
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Outgoing Surgeon General Dr. Jerome Adams last week urged doctors to prescribe the treatments "much more frequently," and told people who test positive to seek them out.

"We need you to ask your provider about monoclonal antibodies as a way of keeping you out of the hospital," Adams said.
"The medications, these therapeutics are not being used as much as I, or the doctors on the task force, or the experts, career experts here in the HHS feel that they should be. I want to remind everyone that we're not helpless in our crusade against the virus."

 

 
 
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"Initially there was a lot of skepticism with these medicines," said Dr. Joshua Ranum, the vice president of the North Dakota Medical Association. "Now there has been a very aggressive public outreach here. I've seen a lot more patient awareness and acceptance and we've seen some pretty dramatic results with efficacy."

 

 
 
 
 

 

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https://www.reuters.com/article/us-health-coronavirus-cdc-response-speci/special-report-how-u-s-cdc-missed-chances-to-spot-covids-silent-spread-idUSKBN29R1E7

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(Reuters) - In early February, 57 people arrived at a Nebraska military base, among the first Americans evacuated from Wuhan, China, the epicenter of the new coronavirus outbreak. U.S. health officials knew very little then about the mysterious new virus, and the quarantined group offered an early opportunity to size up the threat.

The federal government sought help from a team at the University of Nebraska Medical Center, including Dr. James Lawler, an experienced infectious disease specialist. Lawler told Reuters he immediately asked the world-renowned U.S. Centers for Disease Control and Prevention (CDC) for permission to test the quarantined group, deeming it crucial to know whether people without symptoms were infected and could spread the deadly pathogen.

Agency officials worried that detained people couldn’t give proper consent because they might feel coerced into testing. “CDC does not approve this study,” an official at the quarantine site wrote to Lawler in a Feb. 8 email obtained by Reuters. “Please discontinue all contact with the travelers for research purposes.”

 

 

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Soon after balking at testing the returnees from Wuhan, the agency delayed testing asymptomatic passengers among 318 evacuees from the Diamond Princess, a contaminated cruise ship in Japan. In addition, the agency failed at that time to make effective use of outside experts and appeared at times unprepared for the crisis on the ground, lacking adequate personal protective gear and ignoring established protocols, Reuters found.


 

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Major problems emerged soon after Lawler and Callahan arrived in Yokohama on Feb. 14.

The U.S. team, including HHS and other U.S. personnel, had to borrow walkie talkies from Japanese authorities because they didn’t have mobile phones that worked internationally, according to an “after-action” report submitted by Lawler and Callahan in March to HHS and obtained by Reuters.

Japan had to lend the U.S. team basic protective gear because the Americans’ supplies didn’t arrive in time, the report said. Some team members were not trained for handling a “highly contagious disease.”

 

 

 

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4 minutes ago, Jeff said:

"Don't touch that please, your primitive intellect wouldn't understand alloys and compositions and things with... molecular structures."

GeUq.gif

 

KTVU channel 2? My bay area station covering itself in glory again?

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4 minutes ago, RETAC21 said:

That man's diagnosis is strikingly similar to mine's in 1991.

Hodgkin's lymphoma was also the first cancer that could be cured, thanks to that Luftwaffe raid on Bari, and some mustard gas shipping by the USA.

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SO suddenly all of these blue states in the midst of the biggest spike yet of Covid deaths have decided to start releasing lockdowns.  In CA they are doing it but refusing to release the data driving the decision because it would confuse people.  Nothing has changed about the disease or the vaccination pace.  It makes it difficult to believe that it isn't political based on a Democrat in the White House who will start taking the blame for people's destroyed lives.  

If that's the case I seriously hope that every official and administrator who kept lockdowns in place in Oct/Nov/Dec faces criminal trials and long prison stays.  Since las Vegas is reopening schools because of a dramatic increase in kids committing suicide I would be fine with murder trials.  If this was a political call then I cannot imagine the rage that will explode when the public realizes that the tens of millions of lives damaged, the hundreds of thousands of businesses and lives destroyed, and the future of tens of millions of children (nice job damaging the future of the next generation who also has to somehow pay our bills and debt!)  was inflicted upon them to make sure Biden became president.

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1 hour ago, nitflegal said:

SO suddenly all of these blue states in the midst of the biggest spike yet of Covid deaths have decided to start releasing lockdowns.  In CA they are doing it but refusing to release the data driving the decision because it would confuse people.  Nothing has changed about the disease or the vaccination pace.  It makes it difficult to believe that it isn't political based on a Democrat in the White House who will start taking the blame for people's destroyed lives.

Trump will get the blame for all deaths, Biden will get the credit for economic recovery. As for California, obvious the state which has massive IT, pharma, defense, and light manufacturing industries, and the largest public university system in the country, simply doesn't have a population which can grasp basic math and stats.

If that's the case I seriously hope that every official and administrator who kept lockdowns in place in Oct/Nov/Dec faces criminal trials and long prison stays.  Since las Vegas is reopening schools because of a dramatic increase in kids committing suicide I would be fine with murder trials.  If this was a political call then I cannot imagine the rage that will explode when the public realizes that the tens of millions of lives damaged, the hundreds of thousands of businesses and lives destroyed, and the future of tens of millions of children (nice job damaging the future of the next generation who also has to somehow pay our bills and debt!)  was inflicted upon them to make sure Biden became president.

That will never happen, due to the obvious efforts to suppress conservative and libertarian speech.

 

 

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18 minutes ago, Ivanhoe said:

 

This is why if we had a Republican party worth a damn that would be all that they talked about for the next two years.  Seriously, every guest spot on a news show.  Every floor speech.  every social media post.

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14 minutes ago, Mikel2 said:

IMG_4042.jpeg

 

I hope the people in those states will realize that they have been peons in a political game.   Yeah, Good luck with that.

In a way I almost hope that they don't realize.  I don't want to see violence on any level but at the level we could see when every CA/NY/MI/etc failed business owner realizes that their lives and livelihoods were nakedly sacrificed as political pawns?  When every parent realizes that their child's permanently damaged psychology (seriously, the impacts on this generation are not only going to be appalling, we literally have no idea how bad it will be for the lost socialization skillset) was to get Biden in office?  I don't think I'm exaggerating when I say those politicians would need to go into protective custody.

If the Republicans want to get soccer moms and inner city minorities on their side they should push what the left did to their kids as their most monotonous message for the next decade.  Learn from the ruthless efficacy of the Democrats and their planned talking points and their ability to not only stay on message but insert it every single time they speak.

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3 minutes ago, JWB said:

Older story but Fauci...........

Dr. Fauci Backed Controversial Wuhan Lab with U.S. Dollars for Risky Coronavirus Research

https://www.newsweek.com/dr-fauci-backed-controversial-wuhan-lab-millions-us-dollars-risky-coronavirus-research-1500741

I remember reading this.  This has to mean something. 

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Free:

Moderna vaccine protects against British and South African variants, company says

The company has begun developing a new vaccine against the South African variant as a precaution

Quote

The finding was largely encouraging but contained a clear warning sign: Even though the vaccine generated disease-fighting antibodies that worked against the South African variant, that efficacy was diminished. Moderna said there was a reduction in response, prompting the company to design a new potential vaccine that could be added on to the current two-dose regimen.

https://www.washingtonpost.com/health/2021/01/25/covid-vaccine-virus-variant/

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24 minutes ago, JWB said:

Older story but Fauci...........

Dr. Fauci Backed Controversial Wuhan Lab with U.S. Dollars for Risky Coronavirus Research

https://www.newsweek.com/dr-fauci-backed-controversial-wuhan-lab-millions-us-dollars-risky-coronavirus-research-1500741

IIRC, gain-of-function research was originally being performed in CDC labs. But they had a number of safety debacles, so the Obama administration ordered those labs to stop work. Smart thing to do. The CDC then offshored the lab work to the PRC. Not so smart thing to do.

I have been saying for almost a year now that its going to turn out that SARS-CoV-2 was developed by the Wuhan lab as a gain-of-function organism, funded by the CDC.

Note that I am for that kind of research. However, I am staunchly against offshoring it to the PRC. Only 3 outcomes:

  1. An enhanced-function virus is developed, for which only the PRC has a vaccine;
  2. An enhanced-function virus is developed and escapes the lab accidentally;
  3. An enhanced-function virus is developed and is used against adversaries to the PRC.

 

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1 hour ago, nitflegal said:

If the Republicans want to get soccer moms and inner city minorities on their side they should push what the left did to their kids as their most monotonous message for the next decade.  Learn from the ruthless efficacy of the Democrats and their planned talking points and their ability to not only stay on message but insert it every single time they speak.

Well said, but the Rs first need to expunge the quislings.

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3 hours ago, nitflegal said:

SO suddenly all of these blue states in the midst of the biggest spike yet of Covid deaths have decided to start releasing lockdowns.  In CA they are doing it but refusing to release the data driving the decision because it would confuse people.  Nothing has changed about the disease or the vaccination pace.  It makes it difficult to believe that it isn't political based on a Democrat in the White House who will start taking the blame for people's destroyed lives. 

It occurred to me that you are discounting the beneficial effect of having Dr. Jill Biden in the WH.

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